Intrapericardial antibiotics and fibrinolysis to shorten course of antibiotics and prevent constrictive pericarditis in acute purulent pericarditis due to staphylococcus aureus

Intrapericardial fibrinolysis in purulent pericarditis—case report

Purulent pericarditis (PP) continues to result in a very serious prognosis and high mortality. The most serious complication of pericarditis is constriction. Intrapericardial administration of fibrinolytic agents, although controversial, can prevent the development of constrictions. We present the case of a 63-year-old man with purulent inflammation of the right knee who was admitted to the int...

Clinical review: Intrapericardial fibrinolysis in management of purulent pericarditis

Purulent pericarditis (PP) is a potentially life-threatening disease. Reported mortality rates are between 20 and 30%. Constrictive pericarditis occurs over the course of PP in at least 3.5% of cases. The frequency of persistent PP (chronic or recurrent purulent pericardial effusion occurring despite drainage and adequate antibiotherapy) is unknown because this entity was not previously classif...

Intrapericardial streptokinase in purulent pericarditis.

Six consecutive children with proven purulent pericarditis were treated with pericardial irrigation with streptokinase. Mean (SD) 861 (678) ml (range 240-2000) of thick purulent fluid was drained, and five children had complete clearance of the pus within 3-8 days. One child developed intrapericardial haemorrhage with a submitral pseudoaneurysm and underwent patch closure of the neck of the ane...

Management of purulent pericarditis with intrapericardial fibrinolysis: a review

Purulent pericarditis remains a life-threatening pathology. There is no consensus on its medicosurgical management. Nevertheless, total pericardiectomy eradicates focus of infection and provides a better outcome than simple pericardial drainage. Because of high morbidity, intrapericardial fibrinolysis has been considered as a less invasive approach for prevention of persistent and constrictive ...

Progressive Constrictive Pericarditis Shortly after Purulent Pericarditis